- Full text PDF available (1)
- This year (0)
- Last 5 years (1)
- Last 10 years (3)
Journals and Conferences
Despite the dramatic increase in speed of synthesis and biological evaluation of new chemical entities, the number of compounds that survive the rigorous processes associated with drug development is low. Thus, an increased emphasis on thorough ADMET (absorption, distribution, metabolism, excretion and toxicity) studies based on in vitro and in silico… (More)
The quantitative structure activity relationship paradigm provides an excellent avenue for investigating ligand–receptor interactions in medicinal chemistry/toxicology. Lateral validation of models formulated using this approach allows for a cohesive understanding of the mechanistic underpinnings of a specific class of related molecules. The diverse… (More)
This is the obituary for Corwin Hansch, pioneer of the quantitative structure activity relationship (QSAR) paradigm.