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  • Laurent Beck, Y Soumounou, +4 authors Harriet S. Tenenhouse
  • Biology, Medicine
  • The Journal of clinical investigation
  • 1997 (First Publication: 15 March 1997)
  • PEX, a phosphate-regulating gene with homology to endopeptidases on the X chromosome, was recently identified as the candidate gene for X-linked hypophosphatemia. In the present study, we clonedExpand
  • Yan Zhang, Richard McLaughlin, Cynthia Gates Goodyer, Andrea C. LeBlanc
  • Biology, Medicine
  • The Journal of cell biology
  • 2002 (First Publication: 4 February 2002)
  • Extracellular amyloid β peptides (Aβs) have long been thought to be a primary cause of Alzheimer's disease (AD). Now, detection of intracellular neuronal Aβ1–42 accumulation before extracellular AβExpand
  • Duc Minh Le, Arnaud Besson, +5 authors Voon Wee Yong
  • Biology, Medicine
  • The Journal of Neuroscience
  • 2003 (First Publication: 15 May 2003)
  • The presence of reactive astrocytes around glioma cells in the CNS suggests the possibility that these two cell types could be interacting. We addressed whether glioma cells use the astrocyteExpand
  • W. Hartmann, B. Digon-Söntgerath, +8 authors T. Pietsch
  • Medicine, Biology
  • Clinical Cancer Research
  • 2006 (First Publication: 15 May 2006)
  • Purpose: Medulloblastomas represent the most frequent malignant brain tumors of childhood. They are supposed to originate from cerebellar neural precursor cells. Recently, it has been shown thatExpand
  • Eric Paradis, H Douillard, Maria Koutroumanis, Cynthia Gates Goodyer, Andrea M Leblanc
  • Biology, Medicine
  • The Journal of Neuroscience
  • 1996 (First Publication: 1 December 1996)
  • Neuronal apoptosis is a suspected cause of neurodegeneration in Alzheimer’s disease (AD). Increased levels of amyloid β peptide (Aβ) induce neuronal apoptosis in vitro and in vivo. The underlyingExpand
  • Xavier Roucou, Qi liang Guo, Yan Zhang, Cynthia Gates Goodyer, Andrea C. LeBlanc
  • Biology, Medicine
  • Journal of Biological Chemistry
  • 2003 (First Publication: 17 October 2003)
  • Recently, it was observed that reverse-translocated cytosolic PrP and PrP expressed in the cytosol induce rapid death in neurons (Ma, J., Wollmann, R., and Lindquist, S. (2002) Science 298,Expand
  • Giacomo G. Vecil, Peter H. Larsen, +4 authors Voon Wee Yong
  • Biology, Medicine
  • Journal of neuroscience research
  • 2000 (First Publication: 15 July 2000)
  • An acute trauma to the CNS rapidly results in the upregulation of inflammatory cytokines that include interleukin-1 (IL-1). We report here that the levels of several matrix metalloproteinases (MMPs)Expand