Learn More
Exposure of rodents or their cells in culture to low doses of a wide variety of chemical agents, many of which are electrophiles, evokes a coordinated metabolic response that protects these systems against the toxicity (including mutagenicity and carcinogenicity) of higher doses of the same or other electrophiles. This response involves enhanced(More)
Dimethyl fumarate and dimethyl maleate are potent inducers of cytosolic NAD(P)H:(quinone acceptor) oxidoreductase (here designated quinone reductase) activity in Hepa 1c1c7 murine hepatoma cells in culture, whereas fumaric and maleic acids are much less potent, in agreement with the much greater reactivity of the esters as Michael reaction acceptors (P.(More)
A number of researchers have hypothesized that the biomechanical forces associated with cultural cranial deformation can influence the formation of sutural ossicles. However, it is still difficult to make definitive conclusions about this relationship because the effects appear to be quite weak, and contradictory results have been obtained when specific(More)
Tarsal and tarsometatarsal coalitions are malsegmentation errors that result in incomplete division between two or more normally separate bones of the foot. Coalitions may be osseous, characterized by bony union, or non-osseous, in which the affected elements are united by fibrous tissue, cartilage, or some combination of both. Evidence indicates that(More)
Hyperostosis frontalis interna (HFI) is a disease characterized by excess bone growth on the internal lamina of the frontal bone and, occasionally, other cranial bones. Although the disease is fairly common in modern populations, its etiology is poorly understood. Hyperostosis frontalis interna has been identified in antiquity, primarily in the Old World,(More)
Entheseal changes have been widely used in anthropology to study activity patterns, but there is an increasing awareness that ageing is associated with these changes. The aim of this study was to test each feature of the new Coimbra method for its variability, side asymmetry and its relationship with age. In addition to this, an overall relationship with(More)
Dimethyl fumarate and dimethyl maléate are potent inducers of cyto-solic NAD(P)H:(quinone acceptor) oxidoreductase (here designated uni-none reducÃ-ase) activity in Hepa Iclc? murine hepatoma cells in culture, whereas fumarie and maleic acids are much less potent, in agreement with the much greater reactivity of the esters as Michael reaction acceptors(More)
Dimethyl fumarate and dimethyl maléate are potent inducers of cyto-solic NAD(P)H:(quinone acceptor) oxidoreductase (here designated uni-none reducÃ-ase) activity in Hepa Iclc? murine hepatoma cells in culture, whereas fumarie and maleic acids are much less potent, in agreement with the much greater reactivity of the esters as Michael reaction acceptors(More)
  • 1