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BACKGROUND Integration of rapid diagnostic testing via matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) with antimicrobial stewardship team (AST) intervention has the potential for early organism identification, customization of antibiotic therapy, and improvement in patient outcomes. The objective of this study was to assess the(More)
The aim of this study was to determine whether a very high-risk group based on presenting characteristics could be identified in patients with advanced Hodgkin's disease who may benefit from high-dose chemotherapy (HDCT). Between 1975 and 1992, 453 previously untreated patients aged under 60 years who did not progress in the first 6 months after the start(More)
PURPOSE Multi-drug resistance mediated by ATP-binding cassette trans-membrane protein pumps is an important cause of cancer treatment failure. Sulindac has been shown to be a competitive substrate for the clinically important resistance protein, multi-drug resistance protein-1 (MRP-1), and thus might enhance the anti-cancer activity of substrate(More)
Oropharyngeal candidiasis is a very common localized infection of the mucus membranes of the oropharynx that is most commonly caused by the patient's own commensal Candida albicans. It is the most common opportunistic infection affecting patients with the human immunodeficiency virus (HIV) and is also quite common in patients with hematological(More)
STUDY OBJECTIVE To analyze the impact of a comprehensive care bundle directed by an antimicrobial stewardship team (AST) on the management of candidemia. DESIGN Single-center, quasi-experimental study. SETTING A 930-bed academic hospital. PATIENTS Seventy-eight patients with candidemia were evaluated; 41 patients received the candidemia care bundle(More)
— One of the robots under development at the NASAs Jet Propulsion Laboratory (JPL) is the Limbed Excursion Mechanical Utility Robot, or LEMUR. Several of the tasks slated for this robot require computer vision, as a system, to interface with the other systems in the robot, such as walking, body pose adjustment, and manipulation. This paper describes the(More)