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OBJECTIVE The inhibitory proteins, IkappaBs, regulate the activity of nuclear factor kappa-beta (NF-kappaB), which is implicated in tumorigenesis by regulating expression of a variety of genes… Continue Reading
OBJECTIVE To explore the effect of liposomal transfection of cyclin A antisense oligodeoxynucleotide (ASON) on HL-60 cell proliferation and apoptosis. METHODS By liposomal transfection, cyclin A… Continue Reading
OBJECTIVE To study the inhibition effect of cyclin G(1) antisense oligodeoxynucleotides (ASON) on the growth of HL-60 cells in nude mice. METHODS (1) Nude mice were divided into control group,… Continue Reading
OBJECTIVE To investigate the expression of cyclins related gene in HL60 cells before and after arsenic trioxide treatment by gene chip. METHODS Total mRNAs were extracted from untreated or arsenic… Continue Reading