Cs. Szalai

  • Citations Per Year
Learn More
Sir" Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency is an autosomal recessive disorder. The typical symptoms of the disease are fasting intolerance, vomiting, episodes of lethargy and coma, accompanied by hypoketotic hypoglycaemia and medium-chain dicarboxylic aciduria. Unless appropriately treated these acute episodes can be fatal. The commonest(More)
The palmoplantar keratodermas (PPK) are a heterogeneous group of conditions, most frequently inherited in autosomal dominant fashion. A few are well-documented autosomal recessive disorders; other are acquired in association with certain metabolic disorders and malignancies. Recently different point mutations of the keratin 9 (K9) gene have been identified(More)
Objective: Histamine plays an important role in a series of processes including inflammation, allergy, gastric acid secretion, neurotransmission, embryogenesis and in various tumours. Histidine decarboxylase (HDC), the enzyme solely responsible for generation of histamine is expressed in many cells including regenerating and tumour cells. HDC expression is(More)
Sir: The b-chemokine receptor 5 (CCR5) has recently been shown to be a major coreceptor for entry of human immunode®ciency virus-1 (HIV-1)[2]. A 32 base-pair (bp) deletion in the CCR5 coding region results in a non-functional receptor. Homozygotes for the mutation are resistant to infection, even after repeated high-risk exposure [1]. This allele is common(More)
Histamine is involved in physiological reactions including inflammation, allergy, regulation of the gastric acid secretion and special neurophysiological events [1]. Further data suggest that histamine plays a modulatory role in the immune response, e.g. by interacting with the production of various cytokines [2, 3]. In this study, we tested both the effect(More)
  • 1