Cristina Therkildsen

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INTRODUCTION Heredity is estimated to cause at least 20% of colorectal cancer. The hereditary nonpolyposis colorectal cancer subset is divided into Lynch syndrome and familial colorectal cancer type X (FCCTX) based on presence of mismatch repair (MMR) gene defects. PURPOSE We addressed the gene expression signatures in colorectal cancer linked to Lynch(More)
BACKGROUND AND PURPOSE Brain tumors represent a rare and relatively uncharacterized tumor type in Lynch syndrome. METHODS The national Danish Hereditary Nonpolyposis Colorectal Cancer Register was utilized to estimate the cumulative life-time risk for brain tumors in Lynch syndrome, and the mismatch repair (MMR) status in all tumors available was(More)
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