Cristina Rusu

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Signaling output of bone morphogenetic proteins (BMPs) is determined by two sets of opposing interactions, one with heterotetrameric complexes of cell surface receptors, the other with secreted antagonists that act as ligand traps. We identified two mutations (N445K,T) in patients with multiple synostosis syndrome (SYM1) in the BMP-related ligand GDF5.(More)
—We have developed a micromachined flow cell consisting of a flow channel integrated with micropipettes. The flow cell is used in combination with an optical trap setup (optical tweezers) to study mechanical and structural properties of-DNA molecules. The flow cell was realized using silicon micromachining including the so-called buried channel technology(More)
Ring chromosomes are rare entities, usually associated with phenotypic abnormalities in correlation with the loss of genetic material. There are various breakpoints and sometimes there is a dynamic mosaicism that is reflected in clinical features. Most of the ring chromosomes are de novo occurrences. Our study reflects the experience of three Romanian(More)
A plant phenotyping approach was applied to evaluate growth rate of containerized tree seedlings during the precultivation phase following seed germination. A simple and affordable stereo optical system was used to collect stereoscopic red-green-blue (RGB) images of seedlings at regular intervals of time. Comparative analysis of these images by means of a(More)
We present spectroscopic confirmation of two new gravitationally lensed quasars, discovered in the Dark Energy Survey (DES) and Wide-field Infrared Survey Explorer (WISE) based on their multiband photometry and extended morphology in DES images. Images of DES J0115−5244 show a red galaxy with two blue point sources at either side, which are images of the(More)
We investigate the effects of fluidic damping on MEMS packaged energy harvesters using numerical simulations in COMSOL Multiphysics. In particular, we compare two models for including squeeze film damping in the case where the harvester is operating close to a wall; an equivalent mass damping based on approximate modal coefficients and the numerical(More)
We report a 20-year-old female with features evocative of Turner syndrome (short stature, broad trunk, mild webbed neck), dysmorphic face, minor features of holo-prosencephaly (HPE), small hands and feet, excessive hair growth on anterior trunk and intellectual disability. Cytogenetic analysis identified a pseudodicentric 14;18 chromosome. Genome wide(More)
The neuro-cardio-facial-cutaneous syndrome (NCFCS) concept was recently established in order to group a number of hereditary disorders characterized by a variable degree of growth and mental retardation, cardiac defects, dysmorphic facial features and skin abnormalities, and having a common background, germline mutations in genes of the RAS-MAPKinase(More)