Cristina Rubio

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OBJECTIVE Many studies have reported that cognitive ability may be predictive of the functional outcome for patients with schizophrenia. However, no study has prospectively examined these aspects in schizophrenia and bipolar disorders simultaneously. The present study attempted to analyze if neurocognition and clinical status predicts the real-life(More)
BACKGROUND There is growing interest to research neurocognition as a putative endophenotype for subjects with bipolar disorders (BD). The authors sought to review the available literature focused on relatives of subjects with bipolar disorder (BD-Rels) and identify suitable cognitive candidates to endophenotypes or endophenocognitypes. METHOD A systematic(More)
Recently, many reports have consistently demonstrated cognitive deficits in patients with bipolar disorder (BD), but their relationship with symptomatology, specifically psychotic symptoms, remains unclear. Our main hypothesis was that a history of hallucinations and/or delusions in the course of BD-I is associated with severe cognitive deficits. We(More)
There is evidence for an association between structural variants in genes for lissencephaly, which are involved in neuronal migration, and prefrontal cognitive deficits in schizophrenia and bipolar patients. On the basis of these intriguing findings, we analyzed 16 markers located in the lissencephaly critical region (LCR in chromosome 17p13.3) in 124(More)
  • Cristina Rubio, Escudero, Igor Zwir´oscar, Cordón García, D Igor Zwir, D Oscar +12 others
  • 2007
La memoria titulada " Fusion of Knowledge towards the Identification of Genetic Profiles in the Systemic Inflammation Problem " , que presenta Cristina Rubio Escudero para optar al grado de doctor, ha sido realizada dentro del pro
— In this contribution, the biological problem of extracting promoters (composed of two nucleotide sequences, TTGACA and TATAAT, separated by among 15 and 22 pairs of bases) from E. coli DNA sequences is tackled. Classical approaches for this problem, based on considering probabilistic models of the promoter motifs, fail at performing accurate predictions(More)
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