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Human papillomavirus genotype distribution in cervical cancer cases in Spain. Implications for prevention.
Molecular markers of endometrial carcinoma detected in uterine aspirates
- E. Colás, Cristina Pérez, A. Gil-Moreno
- Biology, MedicineInternational Journal of Cancer
- 15 November 2011
The discovery of molecular biomarkers of EC are presented and their utility in uterine aspirates is described and represents the basis for the development of a highly sensitive and specific minimally invasive method for screening ECs.
Comparison of 2 Different PCR-Based Technologies for the Detection of Human Papilloma Virus from Paraffin-Embedded Tissue: Genómica Clinical Arrays Versus SPF10-LiPA25
- Cristina Pérez, J. Klaustermeier, L. Alemany, S. Tous, S. de Sanjosé, J. Velasco
- BiologyDiagnostic molecular pathology : the American…
- 1 March 2012
LiPA25 SPF10-PCR technology may be more adequate than Genómica for the detection of HPV DNA when using FFPE tissue and an important difference between 2 PCR-based methods for detection and genotyping of HPV is highlighted.
Evaluation of p16INK4a Overexpression in a Large Series of Cervical Carcinomas: Concordance With SPF10-LiPA25 PCR
- Cristina Pérez, Marta Castillo, J. Velasco
- BiologyInternational journal of gynecological pathology…
- 1 January 2014
When performed on formalin-fixed paraffin-embedded cervical tissue specimens, the higher positivity rate of p16INK4a immunohistochemistry as compared with HPV DNA testing may allow identifying HPV-related ICC cases in which HPV testing was negative.
Development of a gene expression-based test for the detection of endometrial cancer in uterine aspirates.
The development of a gene expression (GE) based test to detect endometrial cancer (EC) in a multicenter validation study conducted in over 10 different hospitals in Spain is ongoing.