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PURPOSE The purpose of this study is to report the complication profile and safety evaluation of supraselective intra-arterial melphalan chemotherapy in children undergoing treatment with advanced retinoblastoma. METHODS Twelve eyes of 10 children with advanced retinoblastoma (Reese-Ellsworth Group Vb or International Classification Group D) were treated(More)
PURPOSE To follow the treatment history of patients with retinoblastoma to identify the trends in the number of hospital visits over time and the direct cost of medical care as determined by age at diagnosis and selected primary treatment modality. DESIGN An Institutional Review Board (IRB) approved consecutive retrospective case series. MATERIALS AND(More)
PURPOSE The purpose of this study was to report a case of a 7-year-old girl with unilateral, multifocal Reese Ellsworth Stage Vb retinoblastoma who was successfully treated using intraarterial chemotherapy infusion as the primary therapy. METHODS This is an interventional case report. A 7-year-old girl presented with advanced unilateral retinoblastoma.(More)
The purpose of this study was to report significant alterations in orbital vasculature following combined systemic chemoreduction/laser ablation and periocular carboplatin treatment and to discuss treatment implications in two cases of advanced retinoblastoma. Assessment of orbital and ophthalmic vasculature was done following nine cycles of systemic(More)
PURPOSE The purpose of this study was to report significant alterations in orbital vasculature after combined systemic chemoreduction with consolidating external beam radiotherapy treatment in a case of advanced retinoblastoma and to discuss implications for intraarterial melphalan rescue chemotherapy. METHODS We studied the case of a 22-month-old child(More)
PURPOSE To report a case of a boy with bilateral germinal retinoblastoma and Down syndrome who was successfully treated despite a predilection toward chemotoxicity associated with Down syndrome. METHODS A 3-month-old boy presenting with germinal retinoblastoma and Down syndrome was treated with diode laser and systemic carboplatin and low-dose(More)
Although it is well known that a variety of pediatric ocular diseases may clinically resemble retinoblastoma, perhaps of more concern is when the actual tumor mimics seemingly benign ocular lesions. The authors present two cases of retinoblastoma with a Coats' response as evidence of the challenge often encountered in evaluating intraocular malignancies.(More)
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