Cristina Chuva Costa

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Workflow modeling has been able to handle requirements down to the point where the specification gets executed on a specialized engine. Present day information systems, however, pose new challenges. Data and decision logic are spread out across a collection of heterogeneous applications of different ages, provided by various vendors, supported on diverse(More)
Given the increasing importance of inter-organizational networks, business models and their underlying information systems must reflect this reality. Among the challenges that arise in this context are the representation of the relationships between the participating actors, the analysis of the complex balance of interests, and the evaluation of the(More)
The role of human cytomegalovirus (HCMV) in lung transplantation (LT) and drawbacks related to viral quantification in bronchoalveolar lavage (BAL) underline the potential usefulness of investigating other specimens. Thirty-three LT recipients were prospectively studied by HCMV quantitative real time PCR on matched transbronchial biopsy (TBB), BAL, and(More)
Matrix-assisted laser-desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (MS) is a useful tool for rapid identification of microorganisms. Unfortunately, its direct application to positive blood culture is still lacking standardized procedures. In this study, we evaluated an easy- and rapid-to-perform protocol for MALDI-TOF MS direct(More)
Spontaneous delivery through a cervical tear, provoked by prostaglandin-induced uterine contractions, was described in a G2P0 woman with a history of cervical dilatation and uterine curettage. This rare complication with potentially serious maternal-fetal consequences can be predicted by an aberrant cervical response to prostaglandins in parturients with(More)
The way the Internet has connected millions of users at negligible costs has changed playing field for companies. Several stakeholders can now come together in virtual networks to create innovative business models that would be unfeasible in the physical world. However, the more radical the departure from the established models of value creation, the bigger(More)
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