• Publications
  • Influence

Claim Your Author Page
Ensure your research is discoverable on Semantic Scholar. Claiming your author page allows you to personalize the information displayed and manage publications (all current information on this profile has been aggregated automatically from publisher and metadata sources).
  • Ion Cristóbal, Rebeca Manso, +10 authors Jesús García-Foncillas
  • Biology, Medicine
  • Molecular cancer therapeutics
  • 2014 (First Published: 1 April 2014)
  • Protein phosphatase 2A (PP2A) is a tumor suppressor that regulates many signaling pathways crucial for cell transformation. In fact, decreased activity of PP2A has been reported as a recurrentContinue Reading
  • Germán Cuesto, Lilian Enriquez-Barreto, +6 authors Miguel Morales
  • Biology, Medicine
  • The Journal of neuroscience : the official…
  • 2011 (First Published: 23 February 2011)
  • The possibility of changing the number of synapses may be an important asset in the treatment of neurological diseases. In this context, the synaptogenic role of the phosphoinositide-3-kinase (PI3K)Continue Reading
  • Juan Madoz-Gúrpide, Sandra Zazo, +6 authors Federico Cuesta Rojo
  • Medicine
  • Journal of Translational Medicine
  • 2015 (First Published: 1 December 2015)
  • BackgroundActivation of the MET oncogene promotes tumor growth, invasion and metastasis in several tumor types. Additionally, MET is activated as a compensatory pathway in the presence of EGFRContinue Reading
  • Ion Cristóbal, Raul Rincon, +5 authors Jesus García-Foncillas
  • Medicine
  • Clinical cancer research : an official journal of…
  • 2015 (First Published: 15 January 2015)
  • PURPOSE SET is an endogenous PP2A inhibitor that might represent a novel molecular target for antitumor therapy. The aim of this study was to evaluate the molecular effects of SET deregulation andContinue Reading
  • Manuel Dómine, Yann Izarzugaza, +17 authors Jesús García-Foncillas
  • Medicine
  • 2012 (First Published: 20 May 2012)
  • e18069 Background: KRAS mutation are harbored in ~30% of NSCLC patients, and have been described associated with an upregulation of genes involved in angiogenesis, including vascular endothelialContinue Reading
  • 1
  • Ion Cristóbal, Raul Rincon, +5 authors Jesus García-Foncillas
  • Biology, Medicine
  • Biochimica et biophysica acta
  • 2014 (First Published: 1 September 2014)
  • BACKGROUND The tumor suppressor protein phosphatase 2A (PP2A) is frequently inactivated in human cancer and phosphorylation of its catalytic subunit (p-PP2A-C) at tyrosine-307 (Y307) has beenContinue Reading