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The adoption of magnetic hyperthermia as either a stand-alone or adjunct therapy for cancer is still far from being optimised due to the variable performance found in many iron oxide nanoparticle systems, including commercially available formulations. Herein, we present a reproducible and potentially scalable microwave-based method to make stable citric… (More)
The synthesis of iron oxide nanocrystals from reagents taken from high street sources using thermal decomposition of an iron-fatty acid precursor in a high boiling point solvent in the presence of surfactants is presented. The nanocrystals were characterised using a variety of techniques including: electron microscopy, X-ray dispersive spectroscopy,… (More)
A novel strategy for delivering functionalised superparamagnetic iron oxide nanoparticles to the outer surface of pancreatic islet grafts, using chemically modified polymeric nanolayers, has been developed for tracking of engrafted pancreatic islets by magnetic resonance imaging.
Pathogen separation is of great significance for precise detection and prevention of disease outbreaks. For the first time, protein A conjugated with chitosan-coated iron oxide nanoparticles was prepared for pathogen separation at low concentrations from liquid samples. Vibrio cholerae O1 (VO1) bacteria were used for testing the effectiveness of this… (More)
Superparamagnetic iron oxide nanometre scale particles have been utilised as contrast agents to image staked target binding oligonucleotide arrays using MRI to correlate the signal intensity and T(2)* relaxation times in different NMR fluids.