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Ribosome profiling data report on the distribution of translating ribosomes, at steady-state, with codon-level resolution. We present a robust method to extract codon translation rates and protein synthesis rates from these data, and identify causal features associated with elongation and translation efficiency in physiological conditions in yeast. We show(More)
Inspired from biology, in this paper we propose a hybrid firefly method for selecting the optimal solution in semantic Web service composition. In our approach, the search space of the selection method is represented by an Enhanced Planning Graph structure which encodes all the Web service composition solutions for a given user request. As selection(More)
Accurate prediction of RNA pseudoknotted secondary structures from the base sequence is a challenging computational problem. Since prediction algorithms rely on thermodynamic energy models to identify low-energy structures, prediction accuracy relies in large part on the quality of free energy change parameters. In this work, we use our earlier constraint(More)
This paper presents a technique for semantic Web service composition inspired by the behavior of ants. The proposed technique combines a service composition graph model with the ant colony optimization met heuristic to select the optimal composition solution. In our approach, we have considered as selection criteria the QoS attributes of the services and(More)