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AIM To investigate the diagnostic accuracy of acoustic radiation force impulse (ARFI) imaging as a noninvasive method for the assessment of liver fibrosis in chronic hepatitis C (CHC) patients. METHODS We performed a prospective blind comparison of ARFI elastography, APRI index and FibroMax in a consecutive series of patients who underwent liver biopsy(More)
INTRODUCTION A quarter of patients with involuntary weight loss (IWL) have cancer. Inflammation and anemia are associated with cancer, and recent studies showed that red blood cell distribution width (RDW) is a predictor of mortality, including cancer-related death. The aim of this study was to assess the ability of routine hematological and inflammation(More)
BACKGROUND AND AIMS Mucosal healing is an important predictor of disease-related outcome in patients with inflammatory bowel disease (IBD) patients, including those in clinical remission. However, colonoscopy is an invasive procedure and many patients decline repeated endoscopic examinations. We aimed to assess whether noninvasive biomarkers could(More)
BACKGROUND AND STUDY AIMS Intrapulmonary vascular dilatations (IPVDs) are a criterion for the diagnosis of hepatopulmonary syndrome in patients with liver cirrhosis. We aimed to show that IPVDs are more common than suspected in a heterogenous cirrhotic population and to identify new diagnostic parameters. PATIENTS AND METHODS Forty-three consecutive(More)
BACKGROUND & AIMS Good bowel cleansing is essential to achieving optimal endoscopic evaluation of the colon. There are many different regimens available, but none have shown consistently superior results in achieving a clean colon. We compared the efficiency of two regimens with regard to bowel cleansing and patient satisfaction. The study also aimed to(More)
In their study concerning obesity and coronary risk in patients treated with second-generation antipsychotics, Correll et al. [1] wanted to see whether obesity is an independent risk factor for the 10-year risk of coronary heart disease calculated by Framingham method. After excluding the patients with metabolic syndrome and those taking antihypertensive,(More)
AIMS The aim of our study was to assess the clinical and biological parameters associated with Nonalcoholic steatohepatitis (NASH) and to establish the predictors of significant fibrosis in Nonalcoholic fatty liver disease (NAFLD) patients. METHODS We correlated clinical and biochemical parameters with histological features (simple steatosis or(More)
BACKGROUND Many patients who have involuntary weight loss have cancer. The Hernandez prediction rule includes 5 variables (elevated levels of alkaline phosphatase and lactate dehydrogenase, low albumin, high white blood cell count, and age >80 years). The purpose of this study was to evaluate the validity of the prediction rule. METHODS We prospectively(More)
BACKGROUND Structural right ventricular (RV) abnormalities are present in a substantial proportion of patients with hypertrophic cardiomyopathy (HCM), but the trigger for RV hypertrophy remains unclear. The aim of this study was to assess the relationship between RV and left ventricular (LV) remodeling and the impact of biventricular involvement on clinical(More)
SETTING The Professor Dr Matei Bals National Institute of Infectious Diseases, Bucharest, Romania. OBJECTIVE To create a prediction rule to enable clinicians to differentiate patients with tuberculous meningitis (TBM) from those with viral meningitis. DESIGN We retrospectively analysed patients admitted to a tertiary care facility between 2001 and 2011(More)