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Abstract Seven single nucleotide polymorphisms (SNPs) were genotyped in 535 Brazilian children (158 with acute lymphoblastic leukemia [ALL], 74 with acute myeloid leukemia [AML] and 303 controls).Continue Reading
  • Flavio Jose da Costa Ramos, Maria Tereza Cartaxo Muniz, +11 authors Maria S. Pombo-de-Oliveira
  • Medicine
  • Leukemia & lymphoma
  • 2006 (First Publication: 1 January 2006)
  • Methylenetetrahydrofolate reductase (MTHFR) is an essential enzyme in the metabolism of folate. The presence of polymorphisms that reduce the activity of MTHFR has been linked to the multifactorContinue Reading
  • Crisiane Wais Zanrosso, Mariana Emerenciano, +5 authors Maria S. Pombo-de-Oliveira
  • Physics, Medicine
  • 2005 (First Publication: 1 December 2005)
  • As leucemias resultam de uma interacao adversa entre gene-ambiente, com susceptibilidade condicionada, pelo menos em parte, por polimorfismos de multiplos genes. Como a metilenotetrahidrofolatoContinue Reading
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  • Crisiane Wais Zanrosso, Mariana Emerenciano, Bruno Alves de Aguiar Gonçalves, Alessandra Faro, Sérgio Koifman, Maria S. Pombo-de-Oliveira
  • Medicine
  • Cancer Epidemiology, Biomarkers & Prevention
  • 2010 (First Publication: 30 September 2010)
  • Background: Maternal exposure to dipyrone during pregnancy has been associated with risk of infant leukemia (IL). N-Acetyltransferase 2 (NAT2) enzyme acetylates dipyrone, resulting in a detoxifiedContinue Reading
  • M Rodrigues de Amorim, Crisiane Wais Zanrosso, +8 authors Maria S. Pombo-de-Oliveira
  • Medicine
  • Pediatric hematology and oncology
  • 2008 (First Publication: 1 January 2008)
  • Down syndrome (DS) is an important risk factor associated with acute leukemia (AL). The presence of polymorphisms that reduce 5,10-methylenetetrahydrofolate reductase (MTHFR) activity has been linkedContinue Reading