Craig W Goodmurphy

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Most of the members of the superfamily of mammalian small heat shock or stress proteins are abundant in muscles where they play a role in muscle function and maintenance of muscle integrity. One member of this protein superfamily, human HSP27, is rapidly phosphorylated on three serine residues (Ser(15), Ser(78), and Ser(82)) during cellular response to a(More)
OBJECTIVE To assess the accuracy of common anatomic guides for electromyographic needle placement in muscles. DESIGN Blinded study. The dissector identified different needle placements by a random number attached to a wire in the insertion site. SETTING A university anatomy laboratory. CADAVERS Ten cadaver lower limbs. INTERVENTIONS By using(More)
During rotator cuff repairs, it is recommended that the hypovascular tissue edge be resected. To investigate rotator cuff tendon histopathology, we performed immunohistochemistry on 8 surgical and 6 cadaveric specimens. Hoechst nuclear stain and standard hematoxylin-eosin were used for morphologic analysis. Antibody to human von Willebrand factor tagged(More)
Human facial muscles are unique in that they do not cross joints and they function either to open and close the apertures of the face or to tug the skin into intricate movements producing facial expressions. Compared to other skeletal muscles of the body, little is known about the microscopic architecture and organization of facial muscles. It was(More)
INTRODUCTION The purpose of this investigation was to characterize the placement pattern and factors influencing the primary stability of mini-implants in human cadavers. The factors studied were mini-implant length, placement depth, bone density, and bone type. METHODS Sixty standard mini-implants (6, 8, and 10 mm; 20 of each size) were placed into the(More)
From its inception as a tool for prototype development in the early 1980s, three-dimensional (3-D) printing has made inroads into almost every sector of industry, including health care. Medical applications range from extra- and intracorporeal orthopedic devices to complex, temporal reconstructions of patient-specific anatomy that allow operative planning(More)
STUDY DESIGN Measure the accuracy of needle insertion in thoracic muscles of human cadavers. OBJECTIVES Evaluate the effectiveness of known EMG techniques for sampling thoracic innervated muscles. SUMMARY OF BACKGROUND DATA The evaluation of thoracic radiculopathies requires accurate electrodiagnostic techniques for evaluating the thoracic myotomes. (More)
OBJECTIVE To evaluate the safest and most accurate method of diaphragm needle placement for electromyography. DESIGN Single blinded study. SETTING University anatomy laboratory. CADAVERS Five cadavers. INTERVENTIONS Needle placement in the diaphragm by an American Board of Electrodiagnostic Medicine physician, blinded dissection by a doctoral(More)
OBJECTIVE To evaluate the accuracy for three methods for needle insertion into the subscapularis muscle for electromyography, botulinum toxin injection, and phenol nerve block. DESIGN Three needle insertion methods were evaluated by cadaver injection by an American Board of Electrodiagnostic Medicine certified physician. An anatomist, blinded to the(More)
OBJECTIVES We describe a simulation-enhanced ultrasonography (US) curriculum for first-year medical students as part of a comprehensive curricular integration of US skills. Our goal was to assess student knowledge and performance of US and determine their satisfaction with the integrated curriculum. METHODS A committee of basic science, clinical, and(More)