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Gestational age and maternal weight effects on fetal cell‐free DNA in maternal plasma
To determine the effects of gestational age and maternal weight on percent fetal cell‐free DNA (cfDNA) in maternal plasma and the change in fetal cfDNA amounts within the same patient over time.
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Trisomy 13 detection in the first trimester of pregnancy using a chromosome‐selective cell‐free DNA analysis method
To assess the performance of chromosome‐selective sequencing of maternal plasma cell‐free DNA (cfDNA) in non‐invasive prenatal testing for trisomy 13.
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Proposal of Vibrionimonas magnilacihabitans gen. nov., sp. nov., a curved Gram-stain-negative bacterium isolated from lake water.
A mesophilic bacterium appearing as curved rod-shaped cells was isolated from Lake Michigan water. It exhibited highest similarities with Sediminibacterium ginsengisoli DCY13(T) (94.4%);Expand
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Non‐invasive prenatal testing with cell‐free DNA: US physician attitudes toward implementation in clinical practice
The aim of this study was to assess awareness, potential adoption, and current utilization of non‐invasive prenatal testing (NIPT) analysis for common fetal aneuploidies among obstetricians.
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Multiple approaches to data‐mining of proteomic data based on statistical and pattern classification methods
The data‐mining challenge presented is composed of two fundamental problems. Problem one is the separation of forty‐one subjects into two classifications based on the data produced by the massExpand
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Bimatoprost, prostamide activity, and conventional drainage.
PURPOSE Despite structural similarity with prostaglandin F(2 alpha), the ocular hypotensive agent bimatoprost (Lumigan; Allergan, Inc., Irvine, CA) shows unique pharmacology in vitro and functionalExpand
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Delivery of SAR 1118 to the retina via ophthalmic drops and its effectiveness in a rat streptozotocin (STZ) model of diabetic retinopathy (DR).
PURPOSE To determine the pharmacokinetics of SAR 1118, a small-molecule antagonist of leukocyte function-associated antigen (LFA)-1, after administration of ophthalmic drops in normal rats, and toExpand
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Catabolism of premercapturic acid pathway metabolites of naphthalene to naphthols and methylthio-containing metabolites in rats.
[14C]Naphthalene was given orally to rats with cannulated bile ducts and to germ-free rats. Bile and urine from the cannulated rats and urine from the germ-free rats contained no radioactiveExpand
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Single ocular injection of a sustained-release anti-VEGF delivers 6 months pharmacokinetics and efficacy in a primate laser CNV model
A potent anti-vascular endothelial growth factor (VEGF) biologic and a compatible delivery system were co-evaluated for protection against wet age-related macular degeneration (AMD) over a 6monthExpand
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The fetal fraction of cell-free DNA in maternal plasma is not affected by a priori risk of fetal trisomy
Objective: To determine the relationship between a priori risk for fetal trisomy and the fraction of fetal cell-free DNA (cfDNA) in maternal blood. Methods: A comparative analysis on fetal cfDNAExpand
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