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Product innovation is endemic among consumer packaged goods firms, and is an integral component of their marketing strategy. As innovations impact markets, there is a pressing need to develop market response models that can adapt to such changes. Our model copes with the challenges dynamic environments entail: nonstationarity, changes in parameters over(More)
The relatively new field of combinatorial chemistry has enabled researchers to create large mixtures of compounds that can be screened for leads in developing potential drug candidates. The new synthetic method has also created a need for better procedures to analyze the complex mixtures that are generated. The immediate goal in most cases is to verify the(More)
While configuration management systems are generally regarded as useful, their deployment process is not well understood or documented. In this paper, we present a case study in configuration management tool deployment. We describe the motivating factors and both the technical considerations and the social issues involved in this process. Our discussion(More)
A method has been demonstrated for producing accurate, reproducible gradients at low microliter per minute flow-rates suitable for liquid chromatographic-mass spectrometric (LC-MS) applications using capillary chromatography columns. The technique employs a low-cost, well characterized balance-column flow-splitter which can be simply added to a(More)
Our computing environment consists of hundreds of UNIX and NT-based computers. We have a coherent UNIX software installation model that scales comfortably to hundreds of machines. We have spent a great deal of time in the last year learning to understand the software installation and support mechanisms for a similarly large NT infrastructure. In this paper,(More)
Mail administrators will inevitably face a situation where they will need to migrate their users from one server to another, not infrequently migrating to a different service altogether. In 2008, two divisions of Argonne National Laboratory found themselves needing to migrate their users from disparate divisional mail servers to a central, institutional(More)
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