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We explored the consequences for learning through interaction with an educational microworld called Electric Field Hockey (EFH). Like many mi-croworlds, EFH is intended to help students develop a qualitative understanding of the target domain, in this case, the physics of electrical interactions. Through the development and use of a computer model that(More)
The pathophysiology of burning mouth disorder (BMD) is not clearly understood, but central neuropathic mechanisms are thought to be involved. The aim of this study was to gain insight into the pathophysiology associated with BMD by using functional magnetic resonance imaging (fMRI). Areas of brain activation following thermal stimulation of the trigeminal(More)
We report a small yet detailed study where we recorded students completing an object-oriented programming exercise in the context of a CS2 course using Python. All students struggled while completing the assignment, most notably experiencing difficulties with parameters and referencing elements with object-dot notation. While previous research has(More)
We examine two approaches for evaluating category membership within an information taxonomy: card sorting and a simple statistical approach based on the word frequencies of content items. To assess these two approaches, we used card sorting methods to develop a category structure for a web site. Metrics from the card sorting were obtained to predict(More)
OBJECTIVES To propose standardized consensus definitions for important clinical endpoints in transcatheter aortic valve implantation (TAVI), investigations in an effort to improve the quality of clinical research and to enable meaningful comparisons between clinical trials. To make these consensus definitions accessible to all stakeholders in TAVI clinical(More)
OBJECTIVE JC virus (JCV) seropositivity is a risk factor for progressive multifocal leukoencephalopathy (PML) in patients on natalizumab. Accordingly, the JCV serological antibody test is of paramount importance in determining disease risk. METHODS We tested the accuracy of the JCV serum antibody test by comparing the results of JCV serology to JCV(More)
Uterine NK (uNK) cells are abundant in human and murine uteri during decidualization. It is unclear whether precursors of uNK (pre-uNK) cells self-renew or are recruited from other sites. To assess self-renewal of pre-uNK cells, uterine segments from NK cell-competent mice were grafted orthotopically into NK/uNK cell-deficient or wild-type mice. Only in(More)
The miR-15/107 family comprises a group of 10 paralogous microRNAs (miRNAs), sharing a 5' AGCAGC sequence. These miRNAs have overlapping targets. In order to characterize the expression of miR-15/107 family miRNAs, we employed customized TaqMan Low-Density micro-fluid PCR-array to investigate the expression of miR-15/107 family members, and other selected(More)