Craig H. Meyer

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A navigator-gated 3D spiral cine displacement encoding with stimulated echoes (DENSE) pulse sequence for imaging 3D myocardial mechanics was developed. In addition, previously described 2D postprocessing algorithms including phase unwrapping, tissue tracking, and strain tensor calculation for the left ventricle (LV) were extended to 3D. These 3D methods(More)
Skeletal muscle is the most abundant tissue in the body and serves various physiological functions including the generation of movement and support. Whole body motor function requires adequate quantity, geometry, and distribution of muscle. This raises the question: how do muscles scale with subject size in order to achieve similar function across humans?(More)
BACKGROUND Quantitative noninvasive imaging of myocardial mechanics in mice enables studies of the roles of individual genes in cardiac function. We sought to develop comprehensive three-dimensional methods for imaging myocardial mechanics in mice. METHODS A 3D cine DENSE pulse sequence was implemented on a 7T small-bore scanner. The sequence used(More)
Off-resonance effects can cause image blurring in spiral scanning and various forms of image degradation in other MRI methods. Off-resonance effects can be caused by both B0 inhomogeneity and concomitant gradient fields. Previously developed off-resonance correction methods focus on the correction of a single source of off-resonance. This work introduces a(More)
BACKGROUND The purpose was to determine the reproducibility and utility of rest, exercise, and perfusion reserve (PR) measures by contrast-enhanced (CE) calf perfusion magnetic resonance imaging (MRI) of the calf in normal subjects (NL) and patients with peripheral arterial disease (PAD). METHODS Eleven PAD patients with claudication (ankle-brachial index(More)
Field inhomogeneity and susceptibility variations, coupled with a long readout, can result in image blurring in spiral imaging. Many correction methods based on a priori off-resonance information, such as an acquired field map, have been proposed in the literature. Automatic off-resonance correction methods are alternative approaches that estimate a field(More)
Spiral scanning is a promising MRI method, but one limitation is that off-resonance effects can cause image blurring. Most current off-resonance correction methods for spiral imaging require an accurate field map, which is difficult to obtain in many applications. Automatic methods can perform off-resonance correction without acquiring a field map. However,(More)