- Full text PDF available (3)
- This year (0)
- Last 5 years (1)
- Last 10 years (1)
Journals and Conferences
The role for lipopolysaccharide (LPS) and a pristane-induced peritoneal exudate (PIPE) on the in vitro development of murine plasmacytoma was studied. MOPC-315 cell suspensions showed little tendency for colony formation in a soft agar culture medium. Additions of LPS and PIPE were required for maximal colony formation. The LPS effect was dose-dependent… (More)
Bacterial endotoxins administered to BALB/c mice given i.p. mineral oil cause an increased incidence of plasma cell tumors, compared with mice given either oil or antigens alone, or oil plus antigen other than endotoxin. Endotoxin in ng doses was more effective than in mug doses.
2,6,10,14-Tetramethylpentadecane (pristane), s.c. injected simultaneously with plasmacytoma inocula, enhances the transplantability of tumor cells. The effect is dose and time dependent. The enhancement is shown only by plasmacytoma (MOPC-315 and MPC-11) and not by the murine lymphosarcoma and chondrosarcoma tested. Various mechanisms, such as stress and… (More)
nated PIPE. The cellular component of PIPE contained few oil filled macrophages (since most of them had been removed by flotation). Lymphocytes, granubocytes, and plasma cells could also be identified. The total cell counts were about 1 to 2 x iO@cells/mb. Similar preparations were made from CBA/J mice, a strain that does not develop plasmacytomas after… (More)
Small inocula of primary plasma tumor cells which do not transplant i.p. unless recipients are conditioned with pristane do so readily when recipients are given i.p. injections of a peritoneal exudate induced by pristane inoculating, but free of pristane.