Courtenay Browne

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Occupational repetition strain injuries (RSI) are a major, unchecked source of disability in industry and commerce, and have considerable social and economic consequences. The long-term morbidity associated with these injuries is preventable, but a coordinated approach to awareness, diagnosis, management, and prevention has been lacking. Confusing(More)
Intra-articular injection of micro-crystalline corticosteroid is used to treat symptomatic osteoarthritis (OA) of the knee, but its duration of effect and efficacy are uncertain. From the observation that pain in OA of the knee can often be blocked by infiltration of the soft tissues at the patella margin with local anaesthetic, this study investigated an(More)
Forty-three patients in whom treatment with sodium aurothiomalate was discontinued because of adverse reactions that either were relatively severe or recurred on rechallenge received treatment with aurothioglucose in oily base. Thirty-six of them had rheumatoid arthritis, four had psoriatic arthritis and three had juvenile chronic arthritis. Aurothioglucose(More)
The uptake of gold by the red blood cells (RBC) of patients treated with aurothiomalate (GSTM) was greatly potentiated by smoking. The ratios of gold concentrations in RBC to the concentrations in plasma were 0.35 +/- 0.07 (mean +/- SE, n = 14) in smokers and 0.028 +/- 0.003 (n = 23) in non-smokers. Gold uptake by RBC in vitro was also greater in smokers(More)
A study was designed to assess the effects of a standardized instructional videotape on reducing interobserver variability for several commonly used observer dependent outcome measures. During a single day, six rheumatologists independently examined six patients with osteoarthritis (OA) in a predetermined order using a Latin square design, before and after(More)
Treatment terminations with gold sodium thiomalate (GST) in 200 patients with rheumatoid arthritis (RA) were analyzed using the life table method. The termination rate was 27% at 6 months, 48% at 12 months and 84% at 48 months. The major reason for termination was mucocutaneous reaction. Pretreatment clinical and laboratory status of the RA did not(More)
OBJECTIVE To discuss the clinical and social phenomenon of refractory cervicobrachial pain, more popularly known as repetitive strain injury (RSI), from the standpoint of medical knowledge and to present the phenomenon as a problem of chronic musculoskeletal pain in which clinical clues suggest a neuropathic pathogenesis. DATA SOURCES Published articles(More)