Cory J. Stephanson

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Utilizing a novel combinational technique incorporating spectrafluorometry and photosensitization, this analysis determined cell viability and cytotoxicity through the introduction of reactive oxygen species and measurement of plasma membrane integrity. Chinese hamster ovary and mouse hybridoma cells were treated with silica hydride after being(More)
The hydroxyl radical scavenging capacity and efficacy of a novel organosiliceous anionic hydride compound, silica hydride, were quantified by a recently developed method. The method measures a direct relationship between the hydroxyl radical scavenging capability of the antioxidant compound and the linear decrease in signal from a fluorescent(More)
Treatment of Chinese hamster ovary and mouse hybridoma cells with Mega-H brand silica hydride, a marketed antioxidant, after photosensitization with singlet oxygen and hydroxyl/superoxide reactive oxygen species through the use of rose bengal diacetate and malachite green resulted in an effective method of reducing free radical activity by more than 96%(More)
Working as an extension of a newly developed method for a capillary electrophoretic analysis of purine nucleotides, nucleosides, bases, and catabolism, an assay of the differential metabolic properties by a novel organosiliceous anionic hydride compound, silica hydride, was evaluated with Chinese hamster ovary mitochondria using a 50-microm(More)
The hydroxyl radical scavenging capacity and efficacy of two dietary antioxidant supplements, Microhydrin and MegaHydrinTM were quantified by a recently developed method which measures a direct relationship between the hydroxyl radical scavenging capability of the antioxidant compound and the linear decrease in signal from the fluorescent(More)
This study aims to create a scientific foundation for the understanding of the mechanism and associative use between magnesium active hydrogen ions and the parameters of oxidation reduction potential (ORP), biochemical involvement in energy producing intracellular reduction systems and cellular hydration. The first objective is that of direct measurement of(More)
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