Cornelius B. Philip

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Hereditary pasSage of yellow fever virus through mosquito eggs was first investigated by Marchoux and Simond (1906) who reported successful transmission to a human being through the first generation offspring of an infective mosquito. Rosenau and Goldberger failed to confirm this work; in fact none of thirteen susceptible human beings, bitten by mosquitoes(More)
Attempts to obtain passage of yellow fever virus from one generation to the next in A. aegypti were unsuccessful. Subcutaneous injections at varying intervals of a saline emulsion of 200 eggs laid by an infective lot of mosquitoes produced no reaction in six normal M. rhesus monkeys. Negative results were also obtained in five biting and two injection(More)
Five M. rhesus fatally infected with yellow fever virus ran varied and typical courses, death occurring from 82 hours to 10 days after infecting. Batches of A. aegypti were fed daily on each monkey and specimens of blood injected into other animals. By mosquito transfer, the virus was found to be circulating in the peripheral blood 1 or 2 days after the(More)
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