Corinna Wülbeck

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The stereotyped positioning of sensory bristles in Drosophila has been shown to result from complex spatiotemporal regulation of the proneural achaete-scute genes, that relies on an array of cis-regulatory elements and spatially restricted transcriptional activators such as Pannier. Other species of derived schizophoran Diptera have equally stereotyped, but(More)
The Drosophila gene pannier (pnr) has recently been assigned to a new class of selector genes (Calleja, M., Herranz, H., Estella, C., Casal, J., Lawrence, P., Simpson, P. and Morata, G. (2000). Development 127, 3971-3980; (Mann, R. S. and Morata, G. (2000). ANNU: Rev. Cell Dev. Biol. 16, 243-271). It specifies pattern in the dorsal body. On the dorsal notum(More)
The number of achaete-scute genes increased during insect evolution, particularly in the Diptera lineage. Sequence comparison indicates that the four achaete-scute genes of Drosophila result from three independent duplication events. After duplication, the new genes acquired individual expression patterns but, in Drosophila, their products can compensate(More)
 groucho is a Drosophila nuclear protein with structural similarity to the transcriptional repressor tup1. Drosophila groucho forms complexes with bHLH proteins of the hairy-enhancer of split [-E(spl)] family, that then act as repressors, for example downstream of the Notch signalling pathway. We describe the isolation and sequence of two zebrafish groucho(More)
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