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Rotavirus group A G12 genotypes were detected in 3 (1.5%) of 198 stool samples positive for human rotavirus. G12P was present in 2 samples, and a mixed G3G12P was found in 1 sample. Phylogenetic analysis of complete open reading frames of all 11 genomic RNA segments proved their Wa-like genogroup affiliation.
The majority of human group A rotaviruses possess the P VP4 genotype. Recently, a genetically distinct subtype of the P genotype, also known as OP354-like P or lineage P-4, emerged in several countries. However, it is unclear for how long the OP354-like P gene has been circulating in humans and how it has spread. In a global collaborative… (More)