- Full text PDF available (2)
- This year (0)
- Last five years (1)
BACKGROUND Efforts to reduce the impact of group A rotaviruses on human morbidity and mortality rely on oral immunisation with live attenuated or recombinant vaccines. A major challenge in immunisation is the vast inter- and intragenotypic diversity accomplished by circulating rotaviruses. OBJECTIVES To monitor rotavirus inter- and intragenotypic… (More)
The prevalence of different genotypes of hepatitis C virus (HCV) in Ethiopia is not known. HCV genotypes influence the response to therapy with alpha-interferon alone or in combination with ribavirin. A cross sectional study was conducted on attendees of voluntary counseling and testing center. Serum samples from 1,954 (734 HIV positive and 1,220 HIV… (More)
Rotavirus group A G12 genotypes were detected in 3 (1.5%) of 198 stool samples positive for human rotavirus. G12P was present in 2 samples, and a mixed G3G12P was found in 1 sample. Phylogenetic analysis of complete open reading frames of all 11 genomic RNA segments proved their Wa-like genogroup affiliation.
The majority of human group A rotaviruses possess the P VP4 genotype. Recently, a genetically distinct subtype of the P genotype, also known as OP354-like P or lineage P-4, emerged in several countries. However, it is unclear for how long the OP354-like P gene has been circulating in humans and how it has spread. In a global collaborative… (More)
A rare G8P rotavirus, designated GER1H-09, was detected in a stool sample from an infant suffering from repeated episodes of emesis for 2 days without diarrhea. Sequencing of all genomic RNA segments was performed, and complete coding sequences were determined. The VP7 amino acid sequence revealed a close phylogenetic relationship to human G8P and… (More)