Corina Melzer

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One of the most promising avenues for compiling connectivity data originates from the notion that individual brain regions maintain individual connectivity profiles; the functional repertoire of a cortical area ("the functional fingerprint") is closely related to its anatomical connections ("the connectional fingerprint") and, hence, a segregated cortical(More)
One of the most promising avenues for compiling connectivity data originates from the notion that individual brain regions maintain individual connectivity profiles; the functional repertoire of a cortical area ("the functional fingerprint") is closely related to its anatomical connections ("the connectional fingerprint") and, hence, a segregated cortical(More)
Basal ganglia and the cerebellum are part of a densely interconnected network. While both subcortical structures process information in basically segregated loops that primarily interact in the neocortex, direct subcortical interaction has been recently confirmed by neuroanatomical studies using viral transneuronal tracers in non-human primate brains. The(More)
One of the most promising avenues for compiling anatomical brain connectivity data arises from diffusion magnetic resonance imaging (dMRI). dMRI provides a rather novel family of medical imaging techniques with broad application in clinical as well as basic neu-roscience as it offers an estimate of the brain's fiber structure completely non-invasively and(More)
The ability to temporarily store and manipulate information in working memory is a hallmark of human intelligence and differs considerably across individuals, but the structural brain correlates underlying these differences in working memory capacity (WMC) are only poorly understood. In two separate studies, diffusion MRI data and WMC scores were collected(More)
Several lethal autosomal recessive genes have stable carrier frequencies of about 1:20-30 in certain communities, while being exceedingly rare in other, biologically equally successful communities sharing the same environment. It is shown that this situation could persist indefinitely, without invoking the concepts of heterozygote advantage or epistasis, if(More)
A modification of the standard format of multiple choice question (MCQ) examinations, recently introduced in certain medical schools in this country, is decribed. The scheme allows for the variation of marks allocated to different in the paper, depending upon the relevance, importance and degree of difficulty of each question. However, the manner in which(More)
OBJECTIVE We wanted to identify differences in grey and white matter in essential tremor patients compared to controls in the non-motor domain, using the example of impaired verbal fluency. BACKGROUND A disturbance of verbal fluency in essential tremor patients compared to healthy controls is behaviorally well described. METHODS Voxel-based morphometry(More)