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Evidence against regulation of AMP-activated protein kinase and LKB1/STRAD/MO25 activity by creatine phosphate.
TLDR
It is found that creatine phosphate did not inhibit phosphorylation of either recombinant or purified rat liver AMPK by LKB1, and Creatine phosphate may indirectly modulate AMPK activity by replenishing ATP at the onset of muscle contraction. Expand
AMP-activated protein kinase kinase activity and phosphorylation of AMP-activated protein kinase in contracting muscle of sedentary and endurance-trained rats.
TLDR
The results suggest that AMPKK is activated during electrical stimulation of both trained and nontrained muscle by mechanisms other than covalent modification. Expand