Coralie Hochman

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5-ethoxymethyl-7-fluoro-3-oxo-1,2,3,5-tetrahydrobenzo[4,5] imidazo[1,2a]pyridine-4-N-(2-fluorophenyl)carboxamide) (RWJ-51204) binds selectively and with high affinity (K(i) = 0.2-2 nM) to the benzodiazepine site on GABA(A) receptors. Considering the GABA shift, the intrinsic modulatory activity of RWJ-51204 is lower than that of full agonist anxiolytics(More)
A study was designed to determine if there are changes in the perception of pain when the flow rate and pressure of an injected anesthetic are precisely controlled. Fifty dentists were given contralateral palatal injections. One side was injected with the Wand injector, a new delivery system that uses a microprocessor and an electric motor to precisely(More)
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