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Isolation, structure elucidation, and cytotoxic evaluation of furanonaphthoquinones from in vitro plantlets and cultures of Streptocarpus dunnii.
TLDR
Two new furanonaphthoquinones are reported, along with the known (3R)-7-methoxy-α-dunnione, which demonstrated cytotoxic activity against a range of breast cancer and pancreatic tumor cell lines. Expand
Inhibition of LFA-1 mediated T-cell motility by naphthoquinones.
TLDR
An in vitro T-cell migration assay has been established and indicates the ability of compounds tested to inhibit the inflammatory response by decreasing LFA-1-mediated T- cell motility. Expand