Constantin Spînu

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In the Republic of Moldova, little is known about hepatitis B, C and D virus (HBV, HCV, HDV) genotypes, although the genetic variant may influence the course and outcome of disease. For HBV genotyping, 301 hepatitis B surface antigen (HBsAg)-positive sera collected in 2010 and 2011 from drug users, prison inmates, commercial sex workers, and the general(More)
BACKGROUND The Republic of Moldova is considered a high endemic country with hepatitis B virus infection having a prevalence of AgHBs of 8% and higher. This paper describes the epidemic process and changes in the acute hepatitis B incidence in Moldova from 1966 until 2006. The objective was to evaluate the prophylactic measures that have led to the decline(More)
Results The following modes of transmission were identified: heterosexual – 130 (87.3%) patients and IDUs (injecting drug use) – 19 (12.7%) patients. Out of 149 patients, 94 (63.1%) patients were detected late with CD4 counts <350 cells/cmm, out of which 56 (59.6%) patients were detected very late with CD4 counts <200 cells/cmm. HIV/AIDS infection was(More)
Viral hepatitis, especially those with parenteral and sexual transmission, still remain a major problem of public health, both globally and for the Republic of Moldova, due to wide spreading, endemicity, increased morbidity and mortality and high rate of invalidity following the chronization of infection, but usually neglected by population and public(More)
BACKGROUND Countries in the World Health Organization (WHO) European Region are reporting more severe influenza activity in the 2015-2016 season compared to previous seasons. OBJECTIVES To conduct a rapid risk assessment to provide interim information on the severity of the current influenza season METHODS: Using the WHO manual for rapid risk assessment(More)
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