Constance Michel

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BACKGROUND Although lactulose and polyethylene glycol are osmotic laxatives widely used in the treatment of chronic constipation, no study has been conducted to compare their actions on the colonic bacterial ecosystem, which has an important influence on host health. AIM To assess the effects of lactulose and polyethylene glycol on the composition and(More)
Despite the well-known Dwyer procedure, developed in 1969, comprehensive reports on its use, with long-term follow-up, are relatively scarce. The purposes of this study were to detect eventual late complications and to compare late results with postoperative angular curve correction. This article reports on 21 children operated on between October 1972 and(More)
Asthmaexpert, an expert system (ES), was produced at the special request of several clinicians in order to better understand the medical decisions made clinical experts in managing an asthmatic patient. We describe and evaluate this knowledge base, focusing mainly on assessment of the severity of asthma. After compiling data from a patient, Asthmaexpert(More)
Between 1963 and 1971, Harrington's technique was used by the senior author to operate on 493 scoliotic patients, of which 364 were idiopathic. A total of 276 patients were reexamined, of which 209 were idiopathic cases. All met the following criteria: a follow-up period of at least 10 years; the operation was performed by the same surgeon; and the review(More)
"Asthmaexpert" was produced at the special request of several clinicians in order to obtain a better understanding of the medical decisions taken by clinical experts in the management of asthmatic patients. In order to assess the severity of asthma, a new score called Artificial Intelligence score (AI score), produced by Asthmaexpert, was compared with(More)
The patellar height was measured according to the index of Caton and Deschamps. The normal index equals 1, the patella considered as being high with an index of 1.2 or greater. The authors reviewed 50 patients presenting with such an anomaly in patellar height to verify whether this patella alta said to be idiopathic was simply a radiographic sign or(More)
Sixty Salter innominate osteotomies were analysed retrospectively with a mean post-operative follow-up of five years. The 53 children, suffering from congenital dislocation of the hip discovered at walking age, had initially been treated by Somerville-Petit conservative management. The results were assessed using the Severin classification and showed 80 per(More)
Importance The role of cytoreductive nephrectomy in patients with metastatic renal cancer in the era of targeted therapy is uncertain. Objective To establish the safety and efficacy of upfront pazopanib therapy prior to cytoreductive nephrectomy in previously untreated patients with metastatic clear cell renal cancer. Design, Setting, and Participants(More)