Constance Christ

Learn More
The physiological relevance of naturally occurring IgM-ALA remains to be elucidated. These autoantibodies are present from birth and increase in diverse inflammatory states that are both infectious and noninfectious. Clinical observations showing significantly less acute allograft rejections in recipients having high IgM-ALA levels, led us to investigate(More)
We have generated a large complex library of single chain antibodies based on four individual libraries from each of 50 donors. DNA coding for the heavy and light chain variable domains of the IgM and IgG repertoires was amplified by PCR using two different sets of primers. Each individual library was composed of approximately 1-5x10(7) independent clones(More)
This in vitro study investigates the interaction between aggregation substance (AS), a virulence factor of Enterococcus faecalis, and colonic mucosal fibronectin in normal colon and colon from patients with Crohn's disease. Fibronectin was found to be overexpressed in Crohn's disease compared to normal colon. Compared to E. faecalis OG1X:pAM944(More)
Values of gamma(+/-KCl) over temperature and molality ranges of 10 degrees to 50 degrees C and 0.01 to 1.0 molal were determined with an electromotive-force cell: potas sium-sensitive glass electrode, KCl (molality), Ag-AgCl. A more satisfactory method than is commonly employed was devised for treating the experimental measurements of potential.
Adrenal aldosterone-producing adenomas (APAs) are a main cause for primary aldosteronism leading to arterial hypertension. Physiologically, aldosterone production in the adrenal gland is stimulated by angiotensin II and high extracellular potassium. These stimuli lead to a depolarization of the plasma membrane and, as a consequence, an increase of(More)
Values of the uncorrected optic axial angle (2H(alpha)) of a crystal of the calcium zeolite stellerite (CaAl(2)Si(7)O(l8) . 7H(2)0) immersed in calcium chloride solutions of known activity of water (a(w)) are directly proportional to log a(w). A general relationship between the chemical potential of water in the crystal and the optic axial angle is obeyed.