Conor T. Keane

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Methicillin-resistant Staphylococcus aureus (MRSA) isolates recovered in Irish hospitals between 1971 and 2002 were characterized using multilocus sequence typing (MLST) (n = 130) and SCCmec typing (n = 172). Where atypical SCCmec typing results were obtained, PCR amplification of entire SCCmec elements, analysis of amplimer mobility, and nucleotide(More)
The serotype F phage Phi42 of Staphylococcus aureus is a triple-converting bacteriophage that encodes the staphylokinase gene (sak) and the enterotoxin A gene (entA). Lysogeny results in loss of expression of the chromosomal beta-haemolysin gene (hlb) (negative conversion), the expression of staphylokinase and enterotoxin A (positive conversion), and the(More)
There has been a significant increase in theprevalence of H. pylori resistance to metronidazole inrecent years, while clarithromycin resistance is stillrelatively rare. In this study we assessed: (1) the effect of primary H. pylori resistance tometronidazole and clarithromycin on the clinicalefficacy of a one-week regimen consisting of(More)
Helicobacter pylori is present in up to 87% of patients with nonulcer dyspepsia. This study assessed the effect of eradicatingHelicobacter pylori infection on the symptoms of nonulcer dyspepsia at four weeks and one year after treatment. Dyspepsia was assessed on the frequency and severity of six symptoms [epigastric pain (night and day), nausea and(More)
Lipid malabsorption is a common clinical manifestation of small bowel bacterial overgrowth. Its pathogenesis, however, remains controversial.Bacteroides melaninogenicus ssp.intermedius, an anaerobic bacterium, is commonly isolated from the upper bowl of patients with small intestinal bacterial overgrowth. The effects of a culture supernate of this organism(More)
Recurrence of Helicobacter pylori infectionafter successful eradication occurs and is associatedwith relapse of gastroduodenal diseases. The aims ofthis paper were to assess the incidence and identify the nature and possible causes of recurrence ofthe infection. A broad-based Medline search wasperformed to identify all related publicationsaddressing(More)
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