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MOTIVATION How chromatin folds in three-dimensional (3D) space is closely related to transcription regulation. As powerful tools to study such 3D chromatin conformation, the recently developed Hi-C technologies enable a genome-wide measurement of pair-wise chromatin interaction. However, methods for the detection of biologically meaningful chromatin(More)
A total of 75 male mice were allotted to five groups of 15 each in a completely randomized experimental design to study the effects of probiotics, inorganic selenium, and selenium-enriched probiotics on male fertility in hyperlipidemic status. The mice in group 1 were fed a normal basal diet and served as negative control. The mice in group 2 were fed a(More)
A new fractional-order chaotic system is proposed in this paper, and a list of state trajectories is presented with fractional derivative of different areas. Furthermore , a circuit diagram is studied to realize the fractional-order chaotic system. The new fractional-order chaotic system can be controlled to reach synchronization based on the nonlinear(More)
Genome-wide association studies (GWAS) have identified thousands of genetic variants associated with complex traits and diseases. However, most of them are located in the non-protein coding regions, and therefore it is challenging to hypothesize the functions of these non-coding GWAS variants. Recent large efforts such as the ENCODE and Roadmap Epigenomics(More)
This paper presents 1) algorithms for blood vessels extraction in sclera-conjunctiva images, which can be applied in syndrome differentiation by observing human eyes (named Ocular Diagnostic in Traditional Chinese Medicine), 2) digitization of extracted vessels. First, sclera-conjunctiva region is isolated by optimal threshold segmentation and mathematical(More)
The piezoelectric effect of biological piezoelectric materials promotes bone growth. However, the material should be subjected to stress before it can produce an electric charge that promotes bone repair and reconstruction conducive to fracture healing. A novel method for in vitro experimentation of biological piezoelectric materials with physiological load(More)