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BACKGROUND The dominant viral etiologies responsible for acute respiratory infections (ARIs) are poorly understood, particularly among hospitalized children in resource-limited tropical countries where morbidity and mortality caused by ARIs are highest. Improved etiological insight is needed to improve clinical management and prevention. OBJECTIVES We(More)
In this paper we study enumeration problems for polytopes arising from combinatorial optimization problems. While these polytopes turn out to be quickly intractable for enumeration algorithms designed for general polytopes, tailor-made algorithms using their rich combinato-rial features can exhibit strong performances. The main engine of these combinatorial(More)
The SDP (semidefinite programming) relaxation for general POPs (polynomial optimization problems), which was proposed as a method for computing global optimal solutions of POPs by Lasserre, has become an active research subject recently. We propose a new heuristic method exploiting the equality constraints in a given POP, and strengthen the SDP relaxation(More)
Improved diagnostic tools for rapid detection, quantitation, and subgrouping of human respiratory syncytial virus (RSV) are needed to aid the development and evaluation of novel intervention strategies. A quantitative real-time RT-PCR using specific locked nucleic acid (LNA) probes was developed to identify RSV and to distinguish RSV subgroups A and B (RSV(More)
General QOPs (quadratic optimization problems) have a linear objective function c T x to be maximized over a nonconvex compact feasible region F described by a finite number of quadratic inequalities. Difficulties in solving a QOP arise from the nonconvexity in its quadratic terms. We propose a branch and bound algorithm for QOPs where branching operations(More)
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