Colleen D. Acosta

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OBJECTIVE To investigate the incidence and risk factors associated with uncomplicated maternal sepsis and progression to severe sepsis in a large population-based birth cohort. METHODS This retrospective cohort study used linked hospital discharge and vital statistics records data for 1,622,474 live births in California during 2005-2007. Demographic and(More)
BACKGROUND In light of increasing rates and severity of sepsis worldwide, this study aimed to estimate the incidence of, and describe the causative organisms, sources of infection, and risk factors for, severe maternal sepsis in the UK. METHODS AND FINDINGS A prospective case-control study included 365 confirmed cases of severe maternal sepsis and 757(More)
OBJECTIVES To describe the incidence, characteristics and risk factors for critical care admission with severe maternal sepsis in the UK. DESIGN National cohort study. SETTING 198 critical care units in the UK. PARTICIPANTS 646 pregnant and recently pregnant women who had severe sepsis within the first 24 hours of admission in 2008-2010. PRIMARY AND(More)
OBJECTIVE To estimate the incidence of severe maternal sepsis due to group B Streptococcus (GBS) in the UK, and to investigate the associated outcomes for mother and infant. DESIGN National case-control study. SETTING All UK consultant-led maternity units. PARTICIPANTS 30 women with confirmed or suspected severe GBS sepsis, and 757 control women. (More)
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