Colin McCannel

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PURPOSE To report the rates of endophthalmitis and the spectrum of causative organisms after intravitreal injection of anti-vascular endothelial growth factor agents and possible prevention strategies. METHODS Meta-analysis of the U.S. literature from 2005 to 2009 reporting endophthalmitis bacterial isolates after intravitreal injection of anti-vascular(More)
To describe the occurrence of ocular hypertension in four patients following injection of ranibizumab intravitreally. Case series. Four patients had high intraocular pressure after intravitreal ranibizumab 0.5 mg. Ocular hypertension occurred 1 month after the second ranibizumab injection in patients 1 and 3, and 1 month after the first ranibizumab in(More)
OBJECTIVE To describe the demographics, diagnostic details, therapeutic management, and outcome in patients with primary CNS lymphoma (PCNSL) with ocular involvement. METHODS A retrospective study of 221 patients was assembled from 16 centers in seven countries. Only HIV-negative, immunocompetent patients with brain and ocular lymphoma were included; none(More)
PURPOSE Most uveitis case series have come from tertiary care centers, and the relative frequencies of disorders they report may reflect referral bias. We sought information about the types of uveitis encountered in the general practice of ophthalmology. METHODS We prospectively examined 213 consecutive cases of general uveitis, defined as intraocular(More)
PURPOSE To assess the intraocular pressure (IOP) changes, within the first 30 min after intravitreal injection of 0.1 ml (4 mg) triamcinolone, 0.09 ml (0.3 mg) pegaptanib, and 0.05 ml (1.25 mg) bevacizumab. METHODS Records of patients who received intravitreal triamcinolone, pegaptanib, and bevacizumab and who had their IOP measured post-injection were(More)
Rhegmatogenous retinal detachment occurs in 5%-7% of the population with a peak prevalence between 40 and 80 years of age. The objects of treatment are to create a chorioretinal scar at the site of the retinal tear and to mechanically appose the detached sensory retina to the underlying retinal pigment epithelium. This apposition is achieved by means of(More)
PURPOSE To report the results of same-day triple therapy with reduced fluence photodynamic therapy, intravitreal dexamethasone, and bevacizumab in patients with neovascular age-related macular degeneration. METHODS Retrospective case series. Records of patients who received same-day triple therapy with reduced fluence photodynamic therapy (25 J/cm),(More)
PURPOSE To report the structural and functional changes in acute macular neuroretinopathy (AMN) and their long-term evolution. Multimodal retinal imaging was acquired, including Fourier domain optical coherence tomography (OCT), infrared (IR) reflectance, and near IR autofluorescence (NIA). METHODS In this retrospective observational case series, detailed(More)
PURPOSE To evaluate the rate of infectious endophthalmitis associated with intravitreal injection of bevacizumab, ranibizumab, and pegaptanib sodium. METHODS A retrospective review of patients who received intravitreal injections of bevacizumab, ranibizumab, and pegaptanib sodium was undertaken. Cases of clinical diagnoses of endophthalmitis or suspected(More)
PURPOSE To determine the incidence of full-thickness macular holes in Olmsted County, Minnesota. DESIGN Population-based retrospective chart review (cross-sectional study). PARTICIPANTS Ninety-four eyes of 85 patients who were residents of Olmsted County, Minnesota. METHODS A population-based retrospective chart review was performed for all diagnoses(More)