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  • Lindsay B Tulloch, Viviane Paula Martini, +6 authors William N. Hunter
  • Biology, Medicine
  • Journal of medicinal chemistry
  • 2010 (First Publication: 16 November 2009)
  • Pteridine reductase (PTR1) is a target for drug development against Trypanosoma and Leishmania species, parasites that cause serious tropical diseases and for which therapies are inadequate. WeContinue Reading
  • Rao H. Valivety, Grant A. Johnston, Colin J. Suckling, Peter J Halling
  • Chemistry, Medicine
  • Biotechnology and bioengineering
  • 1991 (First Publication: 5 December 1991)
  • Porcine pancreatic lipase immobilized on celite particles has been employed as a catalyst for the esterification of dodecanol and decanoic acid in a predominantly organic system. Solvent influence onContinue Reading
  • Philip G Humphreys, Paul Bamborough, +12 authors Rabinder K Prinjha
  • Chemistry, Medicine
  • Journal of medicinal chemistry
  • 2017 (First Publication: 9 January 2017)
  • p300/CREB binding protein associated factor (PCAF/KAT2B) and general control nonderepressible 5 (GCN5/KAT2A) are multidomain proteins that have been implicated in retroviral infection, inflammationContinue Reading
  • Lamyaa Al-Riyami, Miguel A. Pineda, +7 authors William Harnett
  • Medicine, Chemistry
  • Journal of medicinal chemistry
  • 2013 (First Publication: 14 November 2013)
  • In spite of increasing evidence that parasitic worms may protect humans from developing allergic and autoimmune diseases and the continuing identification of defined helminth-derived immunomodulatoryContinue Reading
  • Justyna Rzepecka, Michelle L. Coates, +10 authors William Harnett
  • Biology, Medicine
  • International journal for parasitology
  • 2014 (First Publication: 1 August 2014)
  • ES-62, a glycoprotein secreted by the filarial nematode Acanthocheilonema viteae, exhibits anti-inflammatory properties by virtue of covalently attached phosphorylcholine moieties. Screening of aContinue Reading