Colette Fons

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Zinc improves both insulin secretion and insulin sensitivity, and exerts insulin-like effects. We investigated its acute effects on the parameters of glucose assimilation determined with the minimal model technique from frequent sampling intravenous glucose tolerance test (FSIVGTT) in seven healthy volunteers. FSIVGTTs (0.5 g/kg of glucose, followed by 2 U(More)
Serum zinc was measured in 20 adolescent gymnasts (9 boys, 11 girls, age 12–15 yr) explored for detecting possible adverse effects of intense training on pubertal maturation and growth. They had low serum zinc (0.599±0.026 mg/L) when compared to matched control sedentary children (n=118 mean 0.81±0.014p<0.001). Girls had lower zinc than boys (0.557±0.023 vs(More)
A possible role for zinc deficiency in some cases of growth retardation in southern France was investigated. Control values for zinc for 160 children (age=12.5±2.4 yr) are 0.85±0.22 mg/L (mean ±2 SD). Twenty-five children with low serum zinc values (<0.63 mg/L) and 25 matched short children with normal serum zinc values (>0.63 mg/L) were studied. Children(More)
We investigated whether zincuria is associated with microalbuminuria in type I (insulin-dependent) diabetics (IDDM). In 169 IDDM, 215 overnight urine samples were collected for simultaneous assay of zinc and albumin. In 76 samples with excessive microalbuminuria (>15 mg/L), zincuria was higher than in the 139 other samples (0.83±0.06 vs 0.58±0.03(More)
Considering the modified fluidity of blood during numerous kind of stress, the authors studied blood rheology during delivery as an example of a particularly severe stress. The authors measured blood and plasma viscosity and erythrocyte aggregation in 77 pregnant at the following stages of delivery: below 4 cm dilatation; more than 4 cm dilatation; during(More)
We investigated the effects of zinc supplementation in cases of moderate growth retardation in which GH treatment could not be used. Zamic (ZA, an association containing arginine, L-methionine, and zinc; from Aguettant pharmaceuticals) was compared with arginine aspartate (AA) (5 g) in a crossover randomized trial (6 mo of each treatment at random order(More)
Extensive studies of hemorheology of cord blood (drawn just after delivery) have evidentiated a peculiar rheological pattern: less filterable red cells, reduced erythrocyte aggregation, lowered plasma viscosity. This pattern has been suggested to be important for maintaining a sufficient O2 supply to fetal tissues, by avoiding hyperviscosity despite(More)
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