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Digital Quantification of Proteins and mRNA in Single Mammalian Cells.
Absolute quantification of macromolecules in single cells is critical for understanding and modeling biological systems that feature cellular heterogeneity. Here we show extremely sensitive and… Expand
Association of Somatic GNAQ Mutation With Capillary Malformations in a Case of Choroidal Hemangioma
Importance Choroidal hemangiomas are defined by a thickened choroid owing to vessel overgrowth, which may increase the intraocular pressure and lead to glaucoma. Choroidal hemangioma and glaucoma… Expand
Human microvasculature-on-a chip: anti-neovasculogenic effect of nintedanib in vitro
Idiopathic pulmonary fibrosis is characterized by a progressive scarring and stiffening of the peripheral lung tissue that decreases lung function. Over the course of the disease, the lung… Expand
A somatic missense mutation in GNAQ causes capillary malformation
Purpose of review Capillary malformations, the most common type of vascular malformation, are caused by a somatic mosaic mutation in GNAQ, which encodes the G&agr;q subunit of heterotrimeric… Expand