Clifton J. Stephenson

Publications8
h-index5
Citations175
Highly Influential Citations1
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Colorimetric and fluorometric molecularly imprinted polymer sensors and binding assays
This mini review examines the utility of molecularly imprinted polymers (MIPs) in colorimetric and fluorometric sensors and binding assays. The review focuses on the challenges in developing…
Molecularly imprinted polymer sensor arrays.
A fluorescent diastereoselective molecular sensor for 1,2-aminoalcohols based on the rhodamine B lactone-zwitterion equilibrium.
A simple yet highly sensitive diastereoselective fluorescent assay was developed, which can differentiate diastereomeric 1,2-aminoalcohols such as ephedrine, pseudoephedrine, and methylephedrine…
Toward the development of prochelators as fluorescent probes of copper-mediated oxidative stress.
TLDR
A fluorescent sensor prochelator, FlamB (fluorescein hydrizido 2-imidophenylboronic ester), has been developed that selectively probes for copper under conditions of oxidative stress and provides a modest fluorescence increase in response to Cu(2+) but not other metal ions.
Surprising variations in the rate of ring opening for a series of rhodamine lactams with similar equilibrium endpoints
Two red salts derived from yellow 4-cyano-1-methylpyridinium iodide: 1,1′,1″-trimethyl-4,4′,4″-(1,3,5-triazin-2,4,6-triyl)tripyridinium trisiodide and 4-cyano-1-methylpyridinium triiodide
Investigating a Chemoselective Grignard Reaction in an Undergraduate Discovery Lab To Predict Reactivity and Final Products
A discovery-based Grignard experiment that emphasizes several important concepts in organic chemistry is reported. The Grignard reagent from 1-bromo-4-chlorobenzene was prepared and reacted with…
Synthesis, resolution and crystal structures of two enantiomeric rhodamine derivatives
The synthesis of rac-6′-bromo-3′-diethylamino-3H-spiro[2-benzofuran-1,9′-xanthen]-3-one and its resolution into separate enantiomers is described. The structures of the racemate and of the individual…