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Objective: To assess the safety, tolerability, pharmacokinetic and pharmacodynamic effects of BIIB092 (formerly BMS-986168) on free extracellular tau (eTau) after every 4 week intravenous infusions… Continue Reading
Introduction Extracellular tau is hypothesized to mediate the onset and progression of tauopathies, including Alzheimer's disease, progressive supranuclear palsy, and a subset of frontotemporal lobar… Continue Reading
Objective: To assess the safety, tolerability, pharmacokinetics and pharmacodynamics of the novel anti-myostatin adnectin RG6206 (BMS-986089) in a Phase 1b/2 study in ambulatory boys with Duchenne… Continue Reading
Objective: To describe the design of the PASSPORT study (NCT03068468) in progressive supranuclear palsy (PSP), a neurodegenerative disease characterized by atypical Parkinsonism and tau pathology.… Continue Reading