Claus Bornemann

  • Citations Per Year
Learn More
A faster and more convenient method is required for the detection of recombinant erythropoietin (Epo) in human body fluids. In the present study we wanted to elucidate the principal suitability of immunoaffinity capillary electrophoresis (CE) in this respect. CE offers itself as a high-speed, high-throughput technique provided a suitable affinity reagent is(More)
Infection o f Chlorella-like green algae with freshwater phycoviruses is associated with a large and rapid de­ mand for D N A precursors which cannot be met by the algal deoxyribonucleotide-synthesizing enzymes. We have demonstrated in these cells an up to ten-fold in­ crease o f the key enzyme, ribonucleotide reductase, 1 —2 h post infection. The enzyme(More)
Ribonucleotide reductases [EC 1.17.4.] are a group of enzymes which critically contribute to the biosynthesis of deoxyribonucleotides (dNTPs), the monomeric precursors of DNA polymerization. By a radical reaction mechanism, they catalyze the reduction of the ribonucleotides, ADP, GDP, CDP, and UDP, mostly at the diphosphate level, to their deoxy conterparts(More)
  • 1