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Ketoconazole (KET) and zinc pyrithione (ZPT) are compounds active against the Malassezia spp. yeasts, which are believed to play a major role in dandruff and seborrheic dermatitis. We compared the efficacy and safety of KET 2% and ZPT 1% in shampoo formulations for the alleviation of severe dandruff and seborrheic dermatitis. This open randomized,(More)
The proliferative rates of cells of malignant melanomas were studied by autoradiography after incorporation of tritiated thymidine in them. There is a relationship between the proportion of melanomatous cells synthesizing DNA and the maximum thickness of the neoplasm. Our data suggest that there are two biologically distinct steps in the evolution of(More)
BACKGROUND Thigmotropism is a biological characteristic corresponding to the directional growth of cells following topographical guidance cues. This behavior has been shown experimentally with fungal hyphae of both dermatophytes and nondermatophyte molds, as well as with the mycelial phase of the dimorphic yeast Candida albicans. OBJECTIVE AND METHODS We(More)
Skin microrelief alters progressively with age. Wrinkles do not result from these changes but are superimposed upon them. Wrinkles result from structural changes in the epidermis, dermis and hypodermis. Four types of wrinkles can be recognized. Type 1 wrinkles are atrophic. Type 2 wrinkles are elastotic. Type 3 wrinkles are expressional. Type 4 wrinkles are(More)
There are glaring discrepancies in the microanatomical descriptions of cellulite in the literature. We revisited this common skin condition in women with a microscopic examination of 39 autopsy specimens. A control group consisted of 4 women and 11 men showing no evidence of cellulite. The lumpy aspect of the dermohypodermal interface appeared to represent(More)
Cyanoacrylate skin surface stripping is a simple noninvasive approach that is useful in the evaluation of a number of changes affecting the skin during aging and chronic sun exposure. The procedure has proved to be especially valuable in the diagnosis of some inflammatory, xerotic, neoplastic, and dermal atrophic changes. It can also be used to monitor(More)
BACKGROUND During photoaging, the density of melanin chromatophores is heterogeneous in the epidermis. AIMS To define the patterns of pheomelanin-enriched melanotic hypermelanosis of the face in phototype II subjects and to assess the effect of depigmenting agents. Azelaic acid and glycolic acid were tested as well as a soy extract, reported to reduce(More)
BACKGROUND Cellulite occurs to varying degrees on the thighs and buttocks of many otherwise healthy women. Among the many purported treatments for cellulite, only a handful have been tested in clinical trials. OBJECTIVE The aim of this study was to critically explore the reputed effect of topical retinol in the treatment of cellulite. MATERIALS AND(More)
Several studies have reported the association of cutaneous malignant melanomas (MM) with carcinomas. Collision malignancies cases from our files were retrieved. Among a series of 78,000 primary cutaneous cancers, 11 were collision tumors of MM with basal cell carcinoma and 106 were basosquamous carcinomas while no association was found between MM and(More)
Skin surface stripping is a useful and simple diagnostic tool for the diagnosis of a number of diseases that affect the skin during childhood and adolescence. The procedure has proved to be especially valuable in inflammatory, xerotic, and neoplastic conditions as it provides information regarding pathologic changes as well as diagnosis.