Claim Your Author Page
Ensure your research is discoverable on Semantic Scholar. Claiming your author page allows you to personalize the information displayed and manage publications (all current information on this profile has been aggregated automatically from publisher and metadata sources).
Given the repeated failure of amyloid-based approaches in Alzheimer's disease, there is increasing interest in tau-based therapeutics. Although methylthioninium (MT) treatment was found to be… Continue Reading
A poorly understood feature of the tauopathies is their very different clinical presentations. The frontotemporal lobar degeneration (FTLD) spectrum is dominated by motor and emotional/psychiatric… Continue Reading
The ability of phototrophs to colonise different environments relies on robust protection against oxidative stress, a critical requirement for the successful evolutionary transition from water to… Continue Reading
Un procedimiento para convertir proteoliticamente una proteina precursora en un fragmento producto en una linea celular estable, dicha proteina precursora esta asociada con un estado de enfermedad en… Continue Reading
L'invention concerne des procedes visant a induire ou a moduler l'etat pathologique d'une proteine pathologique d'agregation (ADP p. ex. proteine tau) associee a une affection pathologique comportant… Continue Reading
ylated at several disease-relevant epitopes, leading to progressive neuronal dystrophy and formation of RIPA-insoluble tau. AD-like tau hyperphosphorylation was reduced by the tau kinase inhibitors… Continue Reading