Claudia Cimpoiu

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This research presents the results obtained from the separation, identification and quantitative determination of free amino acids from Gingko biloba and Hedera helix leaf extracts, using three modern techniques: thin layer chromatography (TLC), high performance liquid chromatography (HPLC), and gas chromatography-mass spectrometry. The presence of the(More)
European cranberrybush (Viburnum opulus L.) fruits are well known for their biological properties, of which some are due to the presence of anthocyanins in the berries. Current literature provides little information concerning these fruits. The stability of anthocyanins from Viburnum opulus fruits, in aqueous and ethanolic extracts, stored under darkness(More)
Two mathematical models with seven and six parameters have been created for use as methods for identification of the optimum mobile phase in chromatographic separations. A series of chromatographic response functions were proposed and implemented in order to assess and validate the models. The assessment was performed on a set of androstane isomers.(More)
Wine is one of the most consumed beverages over the world containing large quantities of polyphenolic compounds. These compounds are responsible for quality of red wines, influencing the antioxidant activity, astringency, bitterness and colour, their composition in wine being influenced by the varieties, the vintage and the wineries. The aim of the present(More)
In high performance thin layer chromatography some form of optimization is necessary if complete separation of all components is required. The selection of mobile phase composition is one of the most important components of an optimization strategies. The aim of this paper is the separation of the N-alkyl phenothiazine sulfones by high performance thin(More)
Mobile phase optimization is highly important in planar chromatography. Solvent selection based on experience and chromatographic intuition can be very time consuming when applied to complex mixtures. In these cases, more systematic strategies are needed. This paper presents a new mathematical model for the optimization of the mobile phase composition used(More)
The aim of this paper was the analysis of five androstane isomers by thin-layer chromatography (TLC). The choice of proper mobile phase and the optimization of the mobile phase composition are very important because the chromatographic separation is difficult to achieve. In the first step, the proper mobile phase system was chosen from seven elution systems(More)
A total of eight solvent systems used for the separation of 1,4-benzodiazepine mixtures were investigated. The classification of solvent systems was carried out by the numerical taxonomy technique. The selection of optimum solvent system was accomplished on the basis of information quantity and objective function. The method was found to be a rapid and(More)
Modeling of thin-layer chromatographic separation of androstane isomers to find the optimum mobile phase is described in this paper. The isomers of androstane are present in a variety of samples, so achieving their optimum thin-layer chromatographic separation is very important. A mathematical model was developed and tested. The model takes into account the(More)