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The aim of this study was to search for the existence of behavioural states in the human fetus and to describe their developmental course. In a longitudinal study, 14 low-risk fetuses were studied at 2-week intervals from 32 weeks of gestation onward. Fetal body movements as well as fetal eye movements, visualized by means of real-time ultrasonic imaging,(More)
The clinical and urodynamic effects of anterior vaginal repair and Burch colposuspension for correction of stress urinary incontinence were assessed in a prospective study. Ninety women undergoing surgery for the first time because of genuine stress incontinence were studied. A full clinical examination including simultaneous urethrocystometry according to(More)
Cardiac output (CO) and organ flows were measured in five nonpregnant and 14 pregnant unstressed guinea pigs between the thirty-ninth and sixty-fifth postconceptional day by means of radionuclide-labeled microspheres. Blood pressure, heart rate, and cardiac output in nonpregnant animals were 60 torr, 234 bpm, and 248 ml/min, respectively. These parameters(More)
OBJECTIVES We sought to define the prevalence of cardiac involvement in female patients with Anderson-Fabry disease (AFD). BACKGROUND Anderson-Fabry disease is a rare inborn X-linked lysosomal storage disorder. Globotriaosylceramide (Gb(3)), the major substrate of the deficient alpha-galactosidase A enzyme, accumulates progressively in vulnerable cells,(More)
The principal objective of this study was to evaluate the incidence of adjacent-segment degeneration (ASD) in patients who underwent cervical disc arthroplasty (CDA) as compared with anterior cervical discectomy and fusion (ACDF). It is a prospective cohort study of patients with a single-level cervical degenerative disc disease from C3 to C7 who underwent(More)
Degradation of technical nonylphenol (t-NP), known as an endocrine-disrupting compound mixture, was assessed, using the mitosporic fungal strain UHH 1-6-18-4 isolated from nonylphenol-contaminated river water, and a strain of the aquatic hyphomycete Clavariopsis aquatica. GC-MS analysis could resolve 12 peaks attributable to nonyl chain-branched t-NP(More)
Simultaneous urethrocystometry by means of a dual microtransducer catheter was performed according to a precise, standardized technique serially at 8, 16, 28, and 36 weeks of pregnancy and at 8 weeks post partum in 43 healthy nulliparous women. The urethral pressure profile at rest and the effect of stress (cough) on the urethral pressure profile during(More)
An isolation procedure was developed to provide within one day microcystin-LR, a cyclic heptapeptide toxin from Microcystis aeruginosa PCC 7806. After ODS (octadecylsilyl) solid phase extraction, the crude toxin fraction was chromatographed using a strong anion exchange column. The toxin was eluted with 0.02 M ammonium bicarbonate. An at least 95% purity(More)
During hematoma formation following injury, an inflammatory reaction ensues as an initial step in the healing process. As granulation tissue matures, revascularization is a prerequisite for successful healing. The hypothesis of this study was that scarless tissue reconstitution in the regenerative bone healing process is dependent on a balanced immune(More)
Toxin was obtained from the cyanobacterium Microcystis aeruginosa PCC7941 by extracting freeze-dried cells with water-saturated, acidified n-butanol, diethyl ether-water distribution, reversed-phase thin-layer chromatography and silica high-performance liquid chromatography (HPLC). Two toxic peptide fractions resulted from HPLC. One of these fractions was(More)